概述
- 产品名称Anti-GPCR GPR124抗体
参阅全部 GPCR GPR124 一抗 - 描述兔多克隆抗体to GPCR GPR124
- 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
- 种属反应性与反应: Rat, Human
- 免疫原
Synthetic peptide (Human) of 14 amino acids from the central region
- 阳性对照
- Rat Kidney Tissue Lysate Human bladder tissue
性能
- 形式Liquid
- 存放说明Shipped at 4°C. Store at +4°C.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... - 纯度Immunogen affinity purified
- 克隆多克隆
- 同种型IgG
- 研究领域
相关产品
- Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab67280 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 180 kDa (predicted molecular weight: 142 kDa). | |
| ICC/IF | Use a concentration of 20 µg/ml. | |
| IHC-P | Use at an assay dependent concentration. |
靶标
- 功能Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
- 组织特异性Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
- 序列相似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 4 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. - 结构域Binds to DLG1 through its PDZ-binding motif.
- 细胞定位Cell membrane.
- Information by UniProt
-
数据库链接
- Entrez Gene: 25960 Human
- Entrez Gene: 306543 Rat
- Omim: 606823 Human
- SwissProt: Q96PE1 Human
- Unigene: 274136 Human
-
别名
- DKFZp434C211 antibody
- DKFZp434J0911 antibody
- FLJ14390 antibody
see all
Anti-GPCR GPR124 antibody 图像
-
Immunocytochemistry/ Immunofluorescence - Anti-GPCR GPR124 antibody (ab67280)Immunofluorescence of GPCR GPR124 in Human bladder tissue with ab67280 at 20 ug/mL.
-
Western blot - GPCR GPR124 antibody (ab67280)Lane 1 : Anti-GPCR GPR124 antibody (ab67280) at 2 µg/ml
Lane 2 : Anti-GPCR GPR124 antibody (ab67280) at 4 µg/ml
Lane 1 : Rat kidney tissue lysate
Lane 2 : Rat kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size : 142 kDa
Observed band size : 176,180 kDa (why is the actual band size different from the predicted?) -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR124 antibody (ab67280)ab67280 at 5µg/ml staining of GPCR GPR124 in human bladder tissue using IHC-P.
Anti-GPCR GPR124 antibody (ab67280)参考文献
ab67280 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"