Anti-GPCR GPR124抗体(ab198817)
Key features and details
- Rabbit polyclonal to GPCR GPR124
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-GPCR GPR124抗体
参阅全部 GPCR GPR124 一抗 -
描述
兔多克隆抗体to GPCR GPR124 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Rat -
免疫原
Synthetic peptide corresponding to Human GPCR GPR124 (internal sequence). NP_116166.
Database link: Q96PE1 -
阳性对照
- Mouse bladder tissue lysate; Human liver cancer tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab198817于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/100 - 1/300.
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WB |
1/500 - 1/2000. Predicted molecular weight: 143 kDa.
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说明 |
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IHC-P
1/100 - 1/300. |
WB
1/500 - 1/2000. Predicted molecular weight: 143 kDa. |
靶标
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功能
Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube. -
组织特异性
Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. -
序列相似性
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 4 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
结构域
Binds to DLG1 through its PDZ-binding motif. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 25960 Human
- Entrez Gene: 78560 Mouse
- Entrez Gene: 306543 Rat
- Omim: 606823 Human
- SwissProt: Q96PE1 Human
- SwissProt: Q91ZV8 Mouse
- Unigene: 274136 Human
- Unigene: 87046 Mouse
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别名
- DKFZp434C211 antibody
- DKFZp434J0911 antibody
- FLJ14390 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab198817 被引用在 1 文献中.
- Wu H et al. Protective and therapeutic effects of Trianthema portulacastrum against atherosclerosis in male albino rats via G-protein-coupled receptor 124. AMB Express 9:178 (2019). PubMed: 31673813