Anti-GPCR GPR120抗体(ab97272)

概述

  • 产品名称Anti-GPCR GPR120抗体
    参阅全部 GPCR GPR120 一抗
  • 描述
    兔多克隆抗体to GPCR GPR120
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 1 - 41 of Human GPCR GPR120 (NP_859529).

  • 阳性对照
    • WB: HeLa cell lysate IHC-P: Human prostate adenocarcinoma

性能

应用

Our Abpromise guarantee covers the use of ab97272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/500.

靶标

  • 功能Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
  • 组织特异性Abundant expression in the intestinal tract.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰Phosphorylated. FFA stimulation facilitates phosphorylation.
  • 细胞定位Cell membrane. Colocalized with ARRB2 following DHA treatment.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein coupled receptor 120 antibody
    • G protein coupled receptor 129 antibody
    • G protein coupled receptor GT01 antibody
    • G protein coupled receptor PGR 4 antibody
    • G protein coupled receptor PGR4 antibody
    • G-protein coupled receptor 120 antibody
    • G-protein coupled receptor 129 antibody
    • G-protein coupled receptor GT01 antibody
    • G-protein coupled receptor PGR4 antibody
    • GPR 120 antibody
    • GPR 129 antibody
    • GPR120 antibody
    • GPR129 antibody
    • GT01 antibody
    • HGNC:19345 antibody
    • MGC119984 antibody
    • O3FA1_HUMAN antibody
    • O3FAR1 antibody
    • Omega-3 fatty acid receptor 1 antibody
    • PGR 4 antibody
    • PGR4 antibody
    see all

Anti-GPCR GPR120 antibody 图像

  • Anti-GPCR GPR120 antibody (ab97272) at 1/2000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 42 kDa
  • ab97272, at a 1/500 dilution, staining GPCR GPR120 in paraffin embedded Human prostate adenocarcinoma by Immunohistochemical analysis (20X magnification).
  • ab97272, at a 1/500 dilution, staining GPCR GPR120 in paraffin embedded Human prostate adenocarcinoma by Immunohistochemical analysis (40X magnification).

Anti-GPCR GPR120 antibody (ab97272)参考文献

ab97272 has not yet been referenced specifically in any publications.

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Thank you for your inquiry.

The exact immunogen sequence is proprietary information and I also do not have access to it.

But I would like to confirm that I blasted the sequence of the amino acid range of 1 -41and found only one simi...

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