兔多克隆抗体to GPCR GPR116
Synthetic peptide: V CYKHNFNA SS VSWCSKT VDV CCHFTN AANN SVWSP SMKLN LVPG ENITCQ, corresponding to amino acids 620-670 of Human GPCR GPR116
Human breast carcinoma tissue; A549 cells.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride Note: PBS (without Mg2+ and Ca2+)
Concentration information loading...
Immunogen affinity purified
ab111169 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
1/100 - 1/500.
May have a role in the regulation of acid-base balance.
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain. Contains 3 Ig-like (immunoglobulin-like) domains. Contains 1 SEA domain.
Proteolytically cleaved into 2 highly conserved sites: one in the SEA domain and the other in the stalk domain region preceding the first transmembrane. The later 2 subunits, the extracellular subunit and the seven-transmembrane subunit, remain tightly associated and non-covalently linked.
Information by UniProt
G protein coupled receptor 116 antibody
Anti-GPCR GPR116 antibody 图像
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GPCR GPR116 antibody (ab111169)
ab111169 at 1/50 dilution staining GPCR GPR116 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with synthesized peptide.
Immunocytochemistry/ Immunofluorescence - GPCR GPR116 antibody (ab111169)
ab111169 at 1/100 dilution staining GPCR GPR116 in A549 cells by Immunofluorescence. The image on the right is treated with synthesized peptide.
Anti-GPCR GPR116 antibody (ab111169)参考文献
This product has been referenced in:
et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the Gaq-p63RhoGEF-Rho GTPase pathway. Cancer Res 73:6206-18 (2013).
Read more (PubMed: 24008316) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"