概述

  • 产品名称Anti-GPAT4抗体
  • 描述
    兔多克隆抗体to GPAT4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human AGPAT6.

    (Peptide available as ab91636.)

  • 阳性对照
    • This antibody gave a positive signal in human skeletal muscle tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab76707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long-chain fatty acyl-CoAs.
    • 组织特异性Ubiquitous. Relatively high level of expression in skeletal muscle, heart and testis. Relatively low level of expression in lung.
    • 通路Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
    • 序列相似性Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    • 结构域The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
    • 细胞定位Endoplasmic reticulum membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1 acyl sn glycerol 3 phosphate acyltransferase zeta antibody
      • 1 AGP acyltransferase 6 antibody
      • 1 AGPAT 6 antibody
      • 1-acylglycerol-3-phosphate O-acyltransferase 6 antibody
      • 1-AGP acyltransferase 6 antibody
      • 1-AGPAT 6 antibody
      • Acyl-CoA:glycerol-3-phosphate acyltransferase 4 antibody
      • AGPAT6 antibody
      • Glycerol-3-phosphate acyltransferase 4 antibody
      • GPAT4 antibody
      • GPAT4_HUMAN antibody
      • LPAAT zeta antibody
      • LPAAT-zeta antibody
      • Lysophosphatidic acid acyltransferase zeta antibody
      see all

    Anti-GPAT4 antibody 图像

    • Anti-GPAT4 antibody (ab76707) at 1 µg/ml + Human skeletal muscle tissue lysate - total protein (ab29330) at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 52 kDa
      Observed band size : 49 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 10 minutes

    Anti-GPAT4 antibody (ab76707)参考文献

    ab76707 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76707.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"