Anti-GORASP2/GRASP55抗体(ab74579)
Key features and details
- Rabbit polyclonal to GORASP2/GRASP55
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-GORASP2/GRASP55抗体
参阅全部 GORASP2/GRASP55 一抗 -
描述
兔多克隆抗体to GORASP2/GRASP55 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Human GORASP2/GRASP55 (internal sequence).
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阳性对照
- HeLa, HepG2, Jurkat and LOVO cell extracts.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab74579 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab74579于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 47 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 47 kDa. |
靶标
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功能
May be involved in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. -
序列相似性
Belongs to the GORASP family.
Contains 1 PDZ (DHR) domain. -
翻译后修饰
Myristoylated. Myristoylation is essential for the Golgi targeting.
Palmitoylated.
Phosphorylated in mitotic cells. -
细胞定位
Golgi apparatus membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 26003 Human
- Entrez Gene: 70231 Mouse
- Entrez Gene: 113961 Rat
- Omim: 608693 Human
- SwissProt: Q9H8Y8 Human
- SwissProt: Q99JX3 Mouse
- SwissProt: Q9R064 Rat
- Unigene: 431317 Human
see all -
别名
- AW552058 antibody
- DKFZp434D156 antibody
- FLJ13139 antibody
see all
图片
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All lanes : Anti-GORASP2/GRASP55 antibody (ab74579) at 1/500 dilution
Lane 1 : HeLa cell extracts
Lane 2 : HepG2 cell extracts
Lane 3 : Jurkat cell extracts
Lane 4 : LOVO cell extracts
Lane 5 : HeLa cell extracts with immunizing peptide at 10 µg
Lysates/proteins at 10 µg per lane.
Predicted band size: 47 kDa
Observed band size: 47 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab74579 被引用在 2 文献中.
- Park H et al. TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike. Adv Sci (Weinh) 9:e2105320 (2022). PubMed: 35748162
- Noh SH et al. Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR. Autophagy 14:1761-1778 (2018). PubMed: 29969945