概述

  • 产品名称
  • 描述
    兔多克隆抗体to GOLPH2
  • 特异性
    ab92612 will not recognize GOLPH1 or GOLPH3.
  • 经测试应用
    适用于: ICC/IF, WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic 18 amino acid peptide from near the center of Human GOLPH2 (GenBank accession no. EAW62705).

  • 阳性对照
    • Rat brain tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab92612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 45 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能
    Unknown. Cellular response protein to viral infection.
  • 组织特异性
    Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
  • 序列相似性
    Belongs to the GOLM1/CASC4 family.
  • 翻译后修饰
    Glycosylated.
    Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位
    Golgi apparatus > cis-Golgi network membrane. Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA379P1.3 antibody
    • C9orf155 antibody
    • Chromosome 9 open reading frame 155 antibody
    • Golgi membrane protein 1 antibody
    • Golgi membrane protein GP73 antibody
    • Golgi phosphoprotein 2 antibody
    • Golgi protein 73 kD antibody
    • Golgi protein 73kD antibody
    • GOLM 1 antibody
    • GOLM1 antibody
    • GOLM1_HUMAN antibody
    • GOLPH 2 antibody
    • GOLPH2 antibody
    • GP 73 antibody
    • GP73 antibody
    • PSEC0257 antibody
    see all

图片

  • Immunofluorescence of GOLPH2 in rat brain tissue with ab92612 at 20 ug/mL.

  • Immunohistochemistry of rat brain tissue with ab92612 at 2.5 μg/mL.

  • Lane 1 : Anti-GOLPH2 antibody (ab92612) at 0.25 µg/ml
    Lane 2 : Anti-GOLPH2 antibody (ab92612) at 0.5 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 45 kDa

文献

ab92612 has not yet been referenced specifically in any publications.

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