Anti-GOLPH2抗体(ab92612)
Key features and details
- Rabbit polyclonal to GOLPH2
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-GOLPH2抗体
参阅全部 GOLPH2 一抗 -
描述
兔多克隆抗体to GOLPH2 -
宿主
Rabbit -
特异性
ab92612 will not recognize GOLPH1 or GOLPH3. -
经测试应用
适用于: ICC/IF, WB, IHC-Pmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic 18 amino acid peptide from near the center of Human GOLPH2 (GenBank accession no. EAW62705).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab92612于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
Use a concentration of 20 µg/ml.
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WB |
Use a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 45 kDa.
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IHC-P |
Use at an assay dependent concentration.
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说明 |
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ICC/IF
Use a concentration of 20 µg/ml. |
WB
Use a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 45 kDa. |
IHC-P
Use at an assay dependent concentration. |
靶标
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功能
Unknown. Cellular response protein to viral infection. -
组织特异性
Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes. -
序列相似性
Belongs to the GOLM1/CASC4 family. -
翻译后修饰
Glycosylated.
Phosphorylation sites are present in the extracelllular medium. -
细胞定位
Golgi apparatus > cis-Golgi network membrane. Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption. - Information by UniProt
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数据库链接
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别名
- bA379P1.3 antibody
- C9orf155 antibody
- Chromosome 9 open reading frame 155 antibody
see all
图片
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Immunohistochemistry of rat brain tissue with ab92612 at 2.5 μg/mL.
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Immunofluorescence of GOLPH2 in rat brain tissue with ab92612 at 20 ug/mL.
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Lane 1 : Anti-GOLPH2 antibody (ab92612) at 0.25 µg/ml
Lane 2 : Anti-GOLPH2 antibody (ab92612) at 0.5 µg/ml
All lanes : Rat brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 45 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab92612 被引用在 2 文献中.
- Peng Y et al. GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity. Nat Commun 12:7004 (2021). PubMed: 34853313
- Yan J et al. GOLM1 upregulates expression of PD-L1 through EGFR/STAT3 pathway in hepatocellular carcinoma. Am J Cancer Res 10:3705-3720 (2020). PubMed: 33294262