概述

  • 产品名称Anti-GOLPH2抗体
    参阅全部 GOLPH2 一抗
  • 描述
    山羊多克隆抗体to GOLPH2
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    C-NLLDQREKRNHTL

    , corresponding to C terminal amino acids 389-401 of Human GOLPH2

  • 阳性对照
    • Human small intestine tissue, human prostate tissue, human uterus tissue, HEK293 lysate overexpressing Human GOLM1 with C-terminal MYC tag.

性能

应用

Our Abpromise guarantee covers the use of ab110008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 45 kDa.
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml.

靶标

  • 功能Unknown. Cellular response protein to viral infection.
  • 组织特异性Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
  • 序列相似性Belongs to the GOLM1/CASC4 family.
  • 翻译后修饰Glycosylated.
    Phosphorylation sites are present in the extracelllular medium.
  • 细胞定位Golgi apparatus > cis-Golgi network membrane. Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA379P1.3 antibody
    • C9orf155 antibody
    • Chromosome 9 open reading frame 155 antibody
    • Golgi membrane protein 1 antibody
    • Golgi membrane protein GP73 antibody
    • Golgi phosphoprotein 2 antibody
    • Golgi protein 73 kD antibody
    • Golgi protein 73kD antibody
    • GOLM 1 antibody
    • GOLM1 antibody
    • GOLM1_HUMAN antibody
    • GOLPH 2 antibody
    • GOLPH2 antibody
    • GP 73 antibody
    • GP73 antibody
    • PSEC0257 antibody
    see all

Anti-GOLPH2 antibody 图像

  • ab110008, at 3.75 µg/ml, staining GOLPH2 in Human small intestine tissue by immunohistochemistry.
  • ab110008, at 3.75 µg/ml, staining GOLPH2 in Human prostate tissue by immunohistochemistry.
  • ab110008, at 3.75 µg/ml, staining GOLPH2 in Human uterus tissue by immunohistochemistry.
  • Lane 1 : Anti-GOLPH2 antibody (ab110008) at 1 µg/ml
    Lane 2 : Anti-GOLPH2 antibody (ab110008) at 1 mg/ml
    Lane 3 : anti-Myc tag at 1/1000 dilution

    Lane 1 : HEK293 lysate (in RIPA buffer) overexpressing Human GOLM1 with C-terminal MYC tag at 10 µg
    Lane 2 : Mock-transfected HEK293
    Lane 3 : HEK293 lysate (in RIPA buffer) overexpressing Human GOLM1 with C-terminal MYC tag at 10 µg


    Predicted band size : 45 kDa

Anti-GOLPH2 antibody (ab110008)参考文献

ab110008 has not yet been referenced specifically in any publications.

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