概述

  • 产品名称Anti-GNMT抗体
    参阅全部 GNMT 一抗
  • 描述
    小鼠多克隆抗体to GNMT
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human)

  • 阳性对照
    • Human liver tissue lysate and GNMT transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

靶标

  • 功能Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
  • 组织特异性Abundant in liver.
  • 疾病相关Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
  • 序列相似性Belongs to the glycine N-methyltransferase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.1.1.20 antibody
    • Glycine N methyltransferase antibody
    • Glycine N-methyltransferase antibody
    • Gnmt antibody
    • GNMT_HUMAN antibody
    • OTTHUMP00000016412 antibody
    see all

Anti-GNMT antibody 图像

  • Anti-GNMT antibody (ab67509) at 1/1000 dilution + Human liver tissue lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

    Predicted band size : 33 kDa
    Observed band size : 33 kDa
  • All lanes : Anti-GNMT antibody (ab67509) at 1/500 dilution

    Lane 1 : GNMT transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

    Predicted band size : 33 kDa
    Observed band size : 33 kDa

Anti-GNMT antibody (ab67509)参考文献

ab67509 has not yet been referenced specifically in any publications.

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