概述

  • 产品名称
    Anti-GNAL抗体
  • 描述
    兔多克隆抗体to GNAL
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human GNAL aa 60-90 (internal sequence).

  • 阳性对照
    • Human brain tissue. Extracts from LOVO cells.

性能

应用

Our Abpromise guarantee covers the use of ab74049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
ELISA 1/20000.
IHC-P 1/50 - 1/100.

靶标

  • 功能
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
  • 组织特异性
    Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen. Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined.
  • 序列相似性
    Belongs to the G-alpha family. G(s) subfamily.
  • Information by UniProt
  • 数据库链接
    see all
  • 别名
    • Adenylate cyclase stimulating G alpha protein, olfactory type antibody
    • Adenylate cyclase-stimulating G alpha protein antibody
    • DYT25 antibody
    • G alpha olf antibody
    • Gnal antibody
    • GNAL_HUMAN antibody
    • Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type antibody
    • Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type antibody
    • Guanine nucleotide binding protein G(olf) subunit alpha antibody
    • Guanine nucleotide-binding protein G(olf) subunit alpha antibody
    • olfactory type antibody
    see all

图片

  • Western blot - Anti-GNAL antibody (ab74049)
    Western blot - Anti-GNAL antibody (ab74049)
    All lanes : Anti-GNAL antibody (ab74049) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from LOVO cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 44 kDa
    Observed band size: 44 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GNAL antibody (ab74049)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GNAL antibody (ab74049)
    Immunohistochemistry analysis of paraffin-embedded human brain tissue using 1/50 ab74049, in the absence (left) or presence (right) of the immunizing peptide.

文献

This product has been referenced in:
  • Zhang L  et al. Dopamine receptor and Ga(olf) expression in DYT1 dystonia mouse models during postnatal development. PLoS One 10:e0123104 (2015). WB . Read more (PubMed: 25860259) »
  • Griffin CA  et al. MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Dev Cell 17:649-61 (2009). WB ; Mouse . Read more (PubMed: 19922870) »

See all 2 Publications for this product

发表研究结果有使用 ab74049？请让我们知道，以便我们可以引用本数据表中的参考文章。

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