Anti-GMP Synthase抗体(ab113951)

概述

  • 产品名称Anti-GMP Synthase抗体
    参阅全部 GMP Synthase 一抗
  • 描述
    兔多克隆抗体to GMP Synthase
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 600-650 of Human GMP Synthase (NP_003866.1).

  • 阳性对照
    • HeLa whole cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab113951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-5 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
    • 通路Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
    • 疾病相关Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL.
    • 序列相似性Contains 1 glutamine amidotransferase type-1 domain.
      Contains 1 GMP-binding domain.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Glutamine amidotransferase antibody
      • GMP synthase [glutamine hydrolyzing] antibody
      • GMP synthase [glutamine-hydrolyzing] antibody
      • GMP synthetase antibody
      • Gmps antibody
      • GUAA_HUMAN antibody
      • Guanine monphosphate synthetase antibody
      • Guanosine 5' monophosphate synthase antibody
      • MLL/GMPS fusion protein antibody
      see all

    Anti-GMP Synthase antibody 图像

    • Detection of GMP Synthase in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab113951 at 3 µg/mg lysate for IP. An anti-GMP Synthase antibody which recognizes a downstream epitope was used at 1 µg/ml for subsequent western blot detection. Detection: Chemiluminescence with exposure time of 10 seconds.

    Anti-GMP Synthase antibody (ab113951)参考文献

    ab113951 has not yet been referenced specifically in any publications.

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