概述

  • 产品名称
    Anti-GM-CSF抗体[59]
    参阅全部 GM-CSF 一抗
  • 描述
    小鼠单克隆抗体[59] to GM-CSF
  • 特异性
    This antibody reacts with natural and recombinant hGM-CSF It shows no cross-reaction with other human cytokines or growth factors tested such as IL-1 beta , IL-8, IL-16, TGF-beta 1, GM-CSFR, TNF-alpha, and M-CSF.
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified recombinant hGM-CSF (human granulocyte macrophage colony stimulating factor)

  • 阳性对照
  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. At this concentration this antibody will visualize 0.2 µg/lane of hGM-CSF

靶标

  • 功能
    Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
  • 序列相似性
    Belongs to the GM-CSF family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Colony stimulating factor 2 (granulocyte-macrophage) antibody
    • Colony Stimulating Factor 2 antibody
    • Colony stimulating factor antibody
    • Colony-stimulating factor antibody
    • CSF 2 antibody
    • CSF antibody
    • CSF2 antibody
    • CSF2_HUMAN antibody
    • GM-CSF antibody
    • GMCSF antibody
    • Granulocyte Macrophage Colony Stimulating Factor antibody
    • Granulocyte-macrophage colony-stimulating factor antibody
    • MGC131935 antibody
    • MGC138897 antibody
    • MGI1GM antibody
    • Molgramostin antibody
    • Pluripoietin-a antibody
    • Sargramostim antibody
    see all

实验方案

Anti-GM-CSF antibody [59] (ab649)参考文献

This product has been referenced in:
  • Sawada H  et al. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension. J Exp Med 211:263-80 (2014). Read more (PubMed: 24446489) »

See 1 Publication for this product

Product Wall

There is presently no data on whether or not this antibody has any neutralizing or non-neutralizing effects.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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