概述

  • 产品名称Anti-Glypican 3抗体
    参阅全部 Glypican 3 一抗
  • 描述
    兔多克隆抗体to Glypican 3
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide derived from the C-terminus of Human Glypican 3 protein.

  • 阳性对照
    • Human liver cancer tissue.

性能

应用

Our Abpromise guarantee covers the use of ab93880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/50 for 30 mins at RT.
    Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
    • 组织特异性Highly expressed in lung, liver and kidney.
    • 疾病相关Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome type 1 (SGBS1) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    • 序列相似性Belongs to the glypican family.
    • 细胞定位Cell membrane and Secreted > extracellular space.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DGSX antibody
      • Glypican proteoglycan 3 antibody
      • Glypican-3 [Precursor] antibody
      • Gpc3 antibody
      • GPC3_HUMAN antibody
      • GTR2 2 antibody
      • GTR2-2 antibody
      • Heparan sulphate proteoglycan antibody
      • Intestinal protein OCI 5 antibody
      • Intestinal protein OCI-5 antibody
      • MXR7 antibody
      • OCI 5 antibody
      • OCI-5 antibody
      • OCI5 antibody
      • SDYS antibody
      • Secreted glypican-3 antibody
      • SGB antibody
      • SGBS antibody
      • SGBS1 antibody
      see all

    Anti-Glypican 3 antibody 图像

    • ab993880 at 1/50 dilution staining Glypican 3 in Human liver cancer by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    Anti-Glypican 3 antibody (ab93880)参考文献

    ab93880 has not yet been referenced specifically in any publications.

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