Anti-Glycophorin A + B抗体[HIR2] (Phycoerythrin) (ab26016)

概述

  • 产品名称Anti-Glycophorin A + B抗体[HIR2] (Phycoerythrin)
    参阅全部 Glycophorin A + B 一抗
  • 描述
    小鼠单克隆抗体[HIR2] to Glycophorin A + B (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性The antibody recognizes the N-terminal, homologous portion of glycophorins A (GPA) and B (GPB) which are single-pass membrane sialoglycoproteins and it binds strongly to GPA but weakly to GPB.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide N terminal (Human)

性能

应用

Our Abpromise guarantee covers the use of ab26016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 20µl for 106 cells or 100µl whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPA gene consists of 7 exons and has 97% sequence homology with GYPB from the 5' UTR to the coding sequence encoding the first 45 amino acids. GYPB accounts for S, s and U specificities. GPA and GPB provide the cells with a large mucin-like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are resulted from gene recombinations between GYPA and GYPB. These antigens are expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells (mature erythrocytes are characteristically CD235a positive and CD45 and CD71 negative).
    • 细胞定位Type I membrane protein.
    • 数据库链接
    • 别名
      • CD235a antibody
      • CD235b antibody
      • Erythroid lineage specific membrane sialoglycoprotein antibody
      • Glycophorin Erik antibody
      • Glycophorin HeP2 antibody
      • Glycophorin MiI antibody
      • Glycophorin MiIII antibody
      • Glycophorin MiV antibody
      • Glycophorin MiVI antibody
      • Glycophorin MiX antibody
      • Glycophorin SAT antibody
      • Glycophorin Sta type C antibody
      • GPA antibody
      • GPB antibody
      • GPB.NY antibody
      • GPErik antibody
      • GpMiIII antibody
      • GPSAT antibody
      • GYPA antibody
      • GYPB antibody
      • GYPHe.NY antibody
      • HGpMiIII antibody
      • HGpMiV antibody
      • HGpMiVI antibody
      • HGpMiX antibody
      • HGpMiXI antibody
      • HGpSta(C) antibody
      • Mi.V glycoprotein (24 AA) antibody
      • MN antibody
      • MN sialoglycoprotein antibody
      • MNS antibody
      • PAS 2 antibody
      • PAS 3 antibody
      • PAS2 antibody
      • PAS3 antibody
      • Sialoglycoprotein alpha antibody
      • Sialoglycoprotein delta antibody
      • SS active sialoglycoprotein antibody
      • SS antibody
      see all

    Anti-Glycophorin A + B antibody [HIR2] (Phycoerythrin) (ab26016)参考文献

    ab26016 has not yet been referenced specifically in any publications.

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    We have 4, FITC conjugated anti Glycophorin A antibodies.

    http://www.abcam.com/Glycophorin-A-antibody-YTH89-1-FITC-ab28082.html
    http://www.abcam.com/Glycophorin-A-antibody-FITC-ab112201.html
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