Anti-Glycine Receptor alpha 3抗体(ab118924)

概述

  • 产品名称Anti-Glycine Receptor alpha 3抗体
    参阅全部 Glycine Receptor alpha 3 一抗
  • 描述
    兔多克隆抗体to Glycine Receptor alpha 3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 131-180 (SLDLDPSMLD SIWKPDLFFA NEKGANFHEV TTDNKLLRIF KNGNVLYSIR) of Mouse Glycine Receptor alpha 3 (NP_536686).

  • 阳性对照
    • Mouse small intestine lysate

性能

应用

Our Abpromise guarantee covers the use of ab118924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
  • 组织特异性Widely distributed throughout the central nervous system.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub-subfamily.
  • 结构域The N-terminal domain carries structural determinants essential for agonist and antagonist binding. TM2 is thought to form the innert wall of the chloride channel. The cytoplasmic loop is an important determinant of channel inactivation kinetics.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GLRA 3 antibody
    • Glra3 antibody
    • GLRA3_HUMAN antibody
    • Glycine receptor alpha 3 polypeptide antibody
    • Glycine receptor alpha 3 subunit antibody
    • Glycine receptor subunit alpha 3 antibody
    • Glycine receptor subunit alpha-3 antibody
    • Ligand gated ion channel antibody
    see all

Anti-Glycine Receptor alpha 3 antibody 图像

  • Anti-Glycine Receptor alpha 3 antibody (ab118924) at 1 µg/ml + Mouse small intestine lysate at 10 µg

    Predicted band size : 56 kDa

Anti-Glycine Receptor alpha 3 antibody (ab118924)参考文献

ab118924 has not yet been referenced specifically in any publications.

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