Anti-Glycerol kinase抗体(Biotin) (ab34535)

概述

  • 产品名称Anti-Glycerol kinase抗体(Biotin)
    参阅全部 Glycerol kinase 一抗
  • 描述
    山羊多克隆抗体to Glycerol kinase (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: WB, ELISA, Immunomicroscopy, Dot blotmore details
  • 种属反应性
    与反应: Goat
  • 免疫原

    Glycerol kinase, Cellulomonas species.

  • 常规说明

    10-20 Biotin molecules per goat IgG molecule.

性能

应用

Our Abpromise guarantee covers the use of ab34535 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
Immunomicroscopy
Dot blot
  • 应用说明Dot: Use at an assay dependent dilution.
    ELISA: 1/4000 - 1/20000.
    This product has been assayed against 1.0µg of Glycerol kinase in a standard capture ELISA using Peroxidase conjugated streptavidin and ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic-acid]) as a substrate for 30 minutes at RT.
    IM: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 57 kDa.
    Suitable for other antibody based assays using streptavidin or avidin conjugates.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Key enzyme in the regulation of glycerol uptake and metabolism.
    • 组织特异性Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.
    • 通路Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
    • 疾病相关Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only.
    • 序列相似性Belongs to the FGGY kinase family.
    • 细胞定位Mitochondrion outer membrane. Cytoplasm. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.
    • Information by UniProt
    • 别名
      • ATP glycerol 3 phosphotransferase antibody
      • ATP:glycerol 3 phosphotransferase antibody
      • ATP:glycerol 3-phosphotransferase antibody
      • D930012N15Rik antibody
      • GK antibody
      • GK1 antibody
      • GKD antibody
      • GLPK_HUMAN antibody
      • Glycerokinase antibody
      • Glycerol kinase antibody
      • OTTHUMP00000023108 antibody
      • OTTHUMP00000023109 antibody
      • OTTHUMP00000215321 antibody
      see all

    Anti-Glycerol kinase antibody (Biotin) (ab34535)参考文献

    ab34535 has not yet been referenced specifically in any publications.

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