Anti-Glutathione Peroxidase 4抗体(ab116703)

概述

  • 产品名称Anti-Glutathione Peroxidase 4抗体
    参阅全部 Glutathione Peroxidase 4 一抗
  • 描述
    山羊多克隆抗体to Glutathione Peroxidase 4
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    EEPLVIEKDLPHY

    with a Cysteine residue linker, corresponding to C terminal amino acids 184-196 of Human Glutathione Peroxidase 4 (NP_002076.2).

  • 阳性对照
    • Human Testis lysate and tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab116703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 22 kDa.
ELISA 1/16000.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
  • 组织特异性Present primarily in testis.
  • 序列相似性Belongs to the glutathione peroxidase family.
  • 细胞定位Mitochondrion. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glutathione peroxidase 4 antibody
    • GPX 4 antibody
    • GPX-4 antibody
    • GPX4 antibody
    • GPX4_HUMAN antibody
    • GSHPx-4 antibody
    • MCSP antibody
    • mitochondrial antibody
    • PHGPx antibody
    • Phospholipid hydroperoxidase antibody
    • Phospholipid hydroperoxide glutathione peroxidase antibody
    • Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody
    • snGPx antibody
    • snPHGPx antibody
    • Sperm nucleus glutathione peroxidase antibody
    see all

Anti-Glutathione Peroxidase 4 antibody 图像

  • Anti-Glutathione Peroxidase 4 antibody (ab116703) at 0.1 µg/ml + Human Testis lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
  • ab116703, at 2.5 µg/ml, staining Glutathione Peroxidase 4 in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Glutathione Peroxidase 4 antibody (ab116703)参考文献

ab116703 has not yet been referenced specifically in any publications.

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