概述

  • 产品名称
    Anti-Glutathione Peroxidase 3抗体
    参阅全部 Glutathione Peroxidase 3 一抗
  • 描述
    山羊多克隆抗体to Glutathione Peroxidase 3
  • 特异性
    ab59524 may crossreact with epididymis-specific Glutathione peroxidase 5(GPX5) and olfactory epithelium-speciific Glutathione peroxidase 6 (GPX6).
  • 经测试应用
    适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Pig
    预测可用于: Cow, Dog, Human
  • 免疫原

    Synthetic peptide:

    C-NQFGKQEPGENSE

    , corresponding to internal sequence amino acids 102-114 of Human Glutathione Peroxidase 3

  • 阳性对照
    • Mouse Heart, Kidney and Liver lysates.

性能

应用

Our Abpromise guarantee covers the use of ab59524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 25 kDa).
IHC-Fr Use a concentration of 20 µg/ml.

靶标

  • 功能
    Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
  • 组织特异性
    Secreted in plasma.
  • 序列相似性
    Belongs to the glutathione peroxidase family.
  • 翻译后修饰
    The N-terminus is blocked.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Extracellular glutathione peroxidase antibody
    • Glutathione peroxidase 3 (plasma) antibody
    • Glutathione peroxidase 3 antibody
    • GPX 3 antibody
    • GPx P antibody
    • GPx-3 antibody
    • GPx-P antibody
    • GPX3 antibody
    • GPX3_HUMAN antibody
    • GPXP antibody
    • GSHPx 3 antibody
    • GSHPx P antibody
    • GSHPx-3 antibody
    • GSHPx-P antibody
    • Plasma glutathione peroxidase 3 antibody
    • Plasma glutathione peroxidase antibody
    see all

图片

  • ab59524 (20µg/ml) staining of PFA-perfused cryosection of Porcin Kidney following microwave antigen retrieval with citrate buffer pH 3 and CY3-staining showing vesicular staining of the cytoplasm in PCT epithelial cells.

  • Anti-Glutathione Peroxidase 3 antibody (ab59524) at 1 µg/ml + Mouse Heart lysate in RIPA buffer at 35 µg

    Predicted band size : 25 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
    Detected by chemiluminescence

文献

This product has been referenced in:
  • Civantos E  et al. Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway. Diabetes Metab Syndr Obes 10:207-222 (2017). WB ; Rat . Read more (PubMed: 28652790) »
  • Lubieniecka JM  et al. Biomarkers for severity of spinal cord injury in the cerebrospinal fluid of rats. PLoS One 6:e19247 (2011). WB ; Rat . Read more (PubMed: 21559420) »

See all 2 Publications for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab59524.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册