存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 pH: 7.00 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78% PBS, 20% Glycerol, 1% BSA
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纯度 Immunogen affinity purified
纯化说明 ab125869 is purified by antigen-affinity chromatography.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/5000 - 1/20000. Predicted molecular weight: 59 kDa.
Use at an assay dependent concentration.
功能 Regulatory subunit of glucosidase II.
通路 Glycan metabolism; N-glycan metabolism.
疾病相关 Defects in PRKCSH are a cause of polycystic liver disease (PCLD) [MIM:174050]. PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease (ADPKD) [MIM:173900], which in a considerable but uncertain proportion of cases is associated with hepatic cysts.
序列相似性 Contains 2 EF-hand domains. Contains 1 PRKCSH domain.
细胞定位 Endoplasmic reticulum.
Information by UniProt
80K-H protein antibody
AGE-binding receptor 2 antibody
Anti-Glucosidase 2 subunit beta antibody 图像
Anti-Glucosidase 2 subunit beta antibody (ab125869)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"