Anti-Glucosidase 2 subunit beta抗体(ab125869)

概述

  • 产品名称Anti-Glucosidase 2 subunit beta抗体
    参阅全部 Glucosidase 2 subunit beta 一抗
  • 描述
    兔多克隆抗体to Glucosidase 2 subunit beta
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 237-460 of Human Glucosidase 2 subunit beta (P14314).

  • 阳性对照
    • A549, HeLa, HepG2 and HCT116 whole cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab125869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000 - 1/20000. Predicted molecular weight: 59 kDa.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能Regulatory subunit of glucosidase II.
  • 通路Glycan metabolism; N-glycan metabolism.
  • 疾病相关Defects in PRKCSH are a cause of polycystic liver disease (PCLD) [MIM:174050]. PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease (ADPKD) [MIM:173900], which in a considerable but uncertain proportion of cases is associated with hepatic cysts.
  • 序列相似性Contains 2 EF-hand domains.
    Contains 1 PRKCSH domain.
  • 细胞定位Endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 80K-H protein antibody
    • AGE-binding receptor 2 antibody
    • AGE-R2 antibody
    • G19P1 antibody
    • GLU2B_HUMAN antibody
    • Glucosidase 2 subunit beta antibody
    • Glucosidase II beta subunit antibody
    • Glucosidase II subunit beta antibody
    • Hepatocystin antibody
    • PCLD antibody
    • PKCSH antibody
    • PLD1 antibody
    • PRKCSH antibody
    • Protein kinase C substrate 60.1 kDa protein heavy chain antibody
    • Protein kinase C substrate 80 Kda protein antibody
    • Protein kinase C substrate 80K-H antibody
    • Protein kinase C substrate, 80 Kda protein antibody
    see all

Anti-Glucosidase 2 subunit beta antibody 图像

  • All lanes : Anti-Glucosidase 2 subunit beta antibody (ab125869) at 1/10000 dilution

    Lane 1 : A549 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 59 kDa

Anti-Glucosidase 2 subunit beta antibody (ab125869)参考文献

ab125869 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (LNCaP)
Specification LNCaP
Fixative Formaldehyde
Permeabilization No
Blocking step (agent) for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 22°C
Username

Dr. Armen Petrosyan

Verified customer

提交于 Dec 03 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"