Anti-Glucose Transporter GLUT4抗体[1F8] (ab35826)
Key features and details
- Mouse monoclonal [1F8] to Glucose Transporter GLUT4
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG1
概述
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产品名称
Anti-Glucose Transporter GLUT4抗体[1F8]
参阅全部 Glucose Transporter GLUT4 一抗 -
描述
小鼠单克隆抗体[1F8] to Glucose Transporter GLUT4 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Rat Glucose Transporter GLUT4. Partially purified vesicles containing insulin-responsive glucose transporter 4.
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表位
This antibody has been shown to recognise an epitope in the cytoplasmic portion of the molecule. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
1F8 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab35826于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.
5 µg/ml of antibody will detect Glucose Transporter protein contained in 50-200 µg of solubilised membrane. |
说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 56 kDa. 5 µg/ml of antibody will detect Glucose Transporter protein contained in 50-200 µg of solubilised membrane. |
靶标
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功能
Insulin-regulated facilitative glucose transporter. -
组织特异性
Skeletal and cardiac muscles; brown and white fat. -
疾病相关
Diabetes mellitus, non-insulin-dependent -
序列相似性
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. -
翻译后修饰
Sumoylated. -
细胞定位
Cell membrane. Endomembrane system. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration. - Information by UniProt
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数据库链接
- Entrez Gene: 20528 Mouse
- SwissProt: P14142 Mouse
- Unigene: 10661 Mouse
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别名
- insulin-responsive antibody
- Glucose transporter GLUT 4 antibody
- Glucose transporter type 4 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (12)
ab35826 被引用在 12 文献中.
- Rahimi R et al. TMF1 is upregulated by insulin and is required for a sustained glucose homeostasis. FASEB J 35:e21295 (2021). PubMed: 33475194
- Li H et al. Mixed conjugated linoleic acid sex-dependently reverses high-fat diet-induced insulin resistance via the gut-adipose axis. FASEB J 35:e21466 (2021). PubMed: 33734496
- Lee K et al. Effect of Dietary Silk Peptide on Obesity, Hyperglycemia, and Skeletal Muscle Regeneration in High-Fat Diet-Fed Mice. Cells 9:N/A (2020). PubMed: 32041272
- Al Koborssy D et al. Modulation of olfactory-driven behavior by metabolic signals: role of the piriform cortex. Brain Struct Funct 224:315-336 (2019). PubMed: 30317390
- Sociali G et al. Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model. FASEB J 31:3138-3149 (2017). PubMed: 28386046