Anti-Glucose Transporter GLUT2抗体(ab111117)

概述

  • 产品名称Anti-Glucose Transporter GLUT2抗体
    参阅全部 Glucose Transporter GLUT2 一抗
  • 描述
    山羊多克隆抗体to Glucose Transporter GLUT2
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human Glucose Transporter GLUT2.

  • 阳性对照
    • Human liver tissue.

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应用

Our Abpromise guarantee covers the use of ab111117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/200.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • 组织特异性Liver, insulin-producing beta cell, small intestine and kidney.
  • 疾病相关Fanconi-Bickel syndrome
  • 序列相似性Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 翻译后修饰N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • liver antibody
    • Glucose Transporter 2 antibody
    • Glucose Transporter GLUT2 antibody
    • Glucose transporter type 2 antibody
    • Glucose transporter type 2 liver antibody
    • Glucose transporter, liver/islet antibody
    • GLUT-2 antibody
    • GLUT2 antibody
    • GTR2_HUMAN antibody
    • GTT2 antibody
    • SLC2A2 antibody
    • Solute carrier family 2 (facilitated glucose transporter) member 2 antibody
    • Solute carrier family 2 facilitated glucose transporter member 2 antibody
    • Solute carrier family 2, facilitated glucose transporter member 2 antibody
    see all

Anti-Glucose Transporter GLUT2 antibody 图像

  • ab111117, at 2.5µg/ml, staining Glucose Transporter GLUT2 in formalin-fixed, paraffin-embedded Human Liver tissue by Immunohistochemistry.
  • ab111117 staining Glucose Transporter GLUT2 in human MCF7 cells by Immunocytochemistry/ Immunofluorescence.
    Cells were fixed in paraformaldehyde, blocked with 1% BSA for 30 minutes at 22°C and then incubated with ab111117 at a 1/200 dilution. The secondary used was ab7123, Donkey polyclonal Secondary Antibody to Goat IgG - H&L (TR), pre-adsorbed, used at a 1/200 dilution.

    See Abreview

Anti-Glucose Transporter GLUT2 antibody (ab111117)参考文献

ab111117 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (MCF7)
Specification MCF7
Fixative Paraformaldehyde
Permeabilization No
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: 22°C
Username

Prof. Ahter Dilsad Sanlioglu

Verified customer

提交于 Jun 21 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"