Anti-Glucose Transporter GLUT1抗体,prediluted (ab15310)


  • 产品名称
    Anti-Glucose Transporter GLUT1抗体,prediluted
    参阅全部 Glucose Transporter GLUT1 一抗
  • 描述
    兔多克隆抗体to Glucose Transporter GLUT1,prediluted
  • 宿主
  • 经测试应用
    适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

  • 阳性对照
    • HepG2 cells, esophagous and breast carcinoma. IF/ICC: HeLa whole cell.



Our Abpromise guarantee covers the use of ab15310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明
    IHC-P: Use at an assay dependent dilution. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
    • 组织特异性
      Expressed at variable levels in many human tissues.
    • 疾病相关
      Defects in SLC2A1 are the cause of glucose transporter type 1 deficiency syndrome (GLUT1DS) [MIM:606777]; also known as blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.
      Defects in SLC2A1 are the cause of dystonia type 18 (DYT18) [MIM:612126]. DYT18 is an exercise-induced paroxysmal dystonia/dyskinesia. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT18 is characterized by attacks of involuntary movements triggered by certain stimuli such as sudden movement or prolonged exercise. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia.
    • 序列相似性
      Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
    • 翻译后修饰
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位
      Cell membrane. Melanosome. Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity) antibody
      • CSE antibody
      • DYT17 antibody
      • DYT18 antibody
      • DYT9 antibody
      • EIG12 antibody
      • erythrocyte/brain antibody
      • Erythrocyte/hepatoma glucose transporter antibody
      • facilitated glucose transporter member 1 antibody
      • Glucose transporter 1 antibody
      • Glucose transporter type 1 antibody
      • Glucose transporter type 1, erythrocyte/brain antibody
      • GLUT antibody
      • GLUT-1 antibody
      • GLUT1 antibody
      • GLUT1DS antibody
      • GLUTB antibody
      • GT1 antibody
      • GTG1 antibody
      • Gtg3 antibody
      • GTR1_HUMAN antibody
      • HepG2 glucose transporter antibody
      • HTLVR antibody
      • Human T cell leukemia virus (I and II) receptor antibody
      • MGC141895 antibody
      • MGC141896 antibody
      • PED antibody
      • RATGTG1 antibody
      • Receptor for HTLV 1 and HTLV 2 antibody
      • SLC2A1 antibody
      • Solute carrier family 2 (facilitated glucose transporter), member 1 antibody
      • Solute carrier family 2 antibody
      • Solute carrier family 2, facilitated glucose transporter member 1 antibody
      see all


    • ICC/IF image of ab15310 stained HeLa cells. The cells were 100% Methanol fixed (5 min) and then incubated in 1%BSA / 10% normal Goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab15310, Neat) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 Goat anti-Rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

    • ab15310 staining Glucose Transporter GLUT1 in human esophagous by Immunohistochemistry (FFPE-sections).


    This product has been referenced in:
    • Sawada S  et al. Expression of GLUT-1 and GLUT-3 in xanthogranulomatous cholecystitis induced a positive result on ¹8F-FDG PET: report of a case. Int Surg 98:372-8 (0). Read more (PubMed: 24229026) »

    See 1 Publication for this product


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