RabMAb

Anti-Glucose 6 Phosphate Dehydrogenase抗体[EPR6291] (ab124738)

概述

  • 产品名称Anti-Glucose 6 Phosphate Dehydrogenase抗体[EPR6291]
    参阅全部 Glucose 6 Phosphate Dehydrogenase 一抗
  • 描述
    兔单克隆抗体[EPR6291] to Glucose 6 Phosphate Dehydrogenase
  • 经测试应用适用于: WB, Flow Cytmore details
    不适用于: ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to residues in Human Glucose 6 Phosphate Dehydrogenase.

  • 阳性对照
    • 293T, MOLT4, HUVEC and HeLa cell lysates; Permeablized HeLa cells.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

应用

Our Abpromise guarantee covers the use of ab124738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa).
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC,IHC-P or IP.
  • 靶标

    • 功能Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
    • 组织特异性Isoform Long is found in lymphoblasts, granulocytes and sperm.
    • 通路Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
    • 疾病相关Anemia, non-spherocytic hemolytic, due to G6PD deficiency
    • 序列相似性Belongs to the glucose-6-phosphate dehydrogenase family.
    • 翻译后修饰Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.
    • Information by UniProt
    • 数据库链接
    • 别名
      • G6PD antibody
      • G6PD_HUMAN antibody
      • G6PD1 antibody
      • G6pdx antibody
      • Glucose 6 phosphate 1 dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase, G6PD antibody
      • Glucose-6-phosphate 1-dehydrogenase antibody
      • MET19 antibody
      • POS10 antibody
      • Zwf1p antibody
      see all

    Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] 图像

    • All lanes : Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] (ab124738) at 1/10000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : MOLT4 cell lysate
      Lane 3 : HUVEC cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 59 kDa
    • ab124738 at 1/10 dilution staining Glucose 6 Phosphate Dehydrogenase in permeablized HeLa cells (red) or a rabbit IgG (negative) (green).

    Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] (ab124738)参考文献

    ab124738 has not yet been referenced specifically in any publications.

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