This antibody gave a positive signal in the following whole cell lysates: Caco2; HepG2; SW480.
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The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa).
This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Belongs to the G-protein coupled receptor 2 family.