- 数据表
- 具体的参考文献 (1)
- 实验方案
概述
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产品名称Anti-GLRB抗体
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描述兔多克隆抗体to GLRB
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宿主Rabbit
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经测试应用适用于: WBmore details
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种属反应性与反应: Mouse, Human
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免疫原
Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 102-132 of Human GLRB (NP_001159532.1, NP_000815.1).
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阳性对照
- Mouse cerebellum tissue lysate
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
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存储溶液Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度Immunogen affinity purified
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纯化说明ab123886 is purified through a protein A column, followed by peptide affinity purification.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
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Positive Controls
应用
Our Abpromise guarantee covers the use of ab123886 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | 1/100 - 1/500. Predicted molecular weight: 56 kDa. |
靶标
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相关性GLRB (Glycine receptor beta) is a neurotransmitter-gated ion channel concentrated within the spinal cord and brainstem. Expression is also observed in several upper brain regions including the cortex, cerebellum, hippocampus and amygdala. Binding of glycine to GLRB increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing), controlling spinal reflexes and locomotor behavior.
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细胞定位Plasma membrane; multi-pass membrane protein.
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数据库链接
- Entrez Gene: 2743 Human
- Entrez Gene: 14658 Mouse
- Omim: 138492 Human
- SwissProt: P48167 Human
- SwissProt: P48168 Mouse
- Unigene: 32973 Human
- Unigene: 275639 Mouse
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别名
- Glycine receptor 58 kDa subunit antibody
- Glycine receptor beta antibody
- Glycine receptor subunit beta antibody
see all
图片
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Western blot - Anti-GLRB antibody (ab123886)Anti-GLRB antibody (ab123886) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg
Predicted band size: 56 kDa
文献
This product has been referenced in:
- James VM et al. Novel missense mutations in the glycine receptor ß subunit gene (GLRB) in startle disease. Neurobiol Dis 52:137-49 (2013). WB ; Human . Read more (PubMed: 23238346) »
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"