Anti-GLRB抗体(ab123886)

概述

• 产品名称
  Anti-GLRB抗体
  参阅全部 GLRB 一抗
• 描述
  兔多克隆抗体to GLRB
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse, Human
  
• 免疫原

  Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 102-132 of Human GLRB (NP_001159532.1, NP_000815.1).

• 阳性对照
  • Mouse cerebellum tissue lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
• 存储溶液
  Preservative: 0.09% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  ab123886 is purified through a protein A column, followed by peptide affinity purification.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • Ligand-Gated Ion Channels
  • Glycine Receptor

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • Mouse brain cerebellum tissue lysate - total protein (ab30173)

应用

靶标

• 相关性
  GLRB (Glycine receptor beta) is a neurotransmitter-gated ion channel concentrated within the spinal cord and brainstem. Expression is also observed in several upper brain regions including the cortex, cerebellum, hippocampus and amygdala. Binding of glycine to GLRB increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing), controlling spinal reflexes and locomotor behavior.
• 细胞定位
  Plasma membrane; multi-pass membrane protein.
• 数据库链接
  • Entrez Gene: 2743 Human
  • Entrez Gene: 14658 Mouse
  • Omim: 138492 Human
  • SwissProt: P48167 Human
  • SwissProt: P48168 Mouse
  • Unigene: 32973 Human
  • Unigene: 275639 Mouse
• 别名
  • Glycine receptor 58 kDa subunit antibody
  • Glycine receptor beta antibody
  • Glycine receptor subunit beta antibody

  • Glycine receptor, beta subunit antibody
  • OTTHUMP00000220896 antibody
  • OTTHUMP00000220897 antibody

  see all

实验方案

• Western blot protocols