Anti-Gli1抗体(ab94927)

概述

  • 产品名称Anti-Gli1抗体
    参阅全部 Gli1 一抗
  • 描述
    兔多克隆抗体to Gli1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from Human Gli1

  • 阳性对照
    • RMS-13 lysate.

性能

应用

Our Abpromise guarantee covers the use of ab94927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 10 µg/ml. Predicted molecular weight: 118 kDa. Note: 1/400 is the suggested starting working dilution.

靶标

  • 功能Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
  • 组织特异性Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract.
  • 序列相似性Belongs to the GLI C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • 翻译后修饰Phosphorylated in vitro by ULK3.
  • 细胞定位Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Gli 1 antibody
    • GLI antibody
    • GLI family zinc finger 1 antibody
    • GLI Kruppel family member 1 antibody
    • gli1 antibody
    • GLI1_HUMAN antibody
    • Glioma associated oncogene 1 antibody
    • Glioma associated oncogene homolog 1 (zinc finger protein) antibody
    • Glioma associated oncogene homolog antibody
    • Glioma-associated oncogene antibody
    • Oncogene GLI antibody
    • Zfp 5 antibody
    • Zfp5 antibody
    • Zinc finger protein GLI 1 antibody
    • Zinc finger protein GLI1 antibody
    see all

Anti-Gli1 antibody 图像

  • Anti-Gli1 antibody (ab94927) at 10 µg/ml + RMS-13 lysate at 15 µg

    Secondary
    Mouse anti-rabbit HRP at 1/200000 dilution

    Predicted band size : 118 kDa

Anti-Gli1 antibody (ab94927)参考文献

ab94927 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply. I am sorry to hear the results have not improved. The only other thing that might help is incubating the primary antibody at room temperature for 4-6 hours. However, if there is no improvement I can replace with the same produ...

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