概述

  • 产品名称Anti-GIRK1抗体
    参阅全部 GIRK1 一抗
  • 描述
    兔多克隆抗体to GIRK1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Guinea pig
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 248-501 of Human GIRK1.

  • 阳性对照
    • A431, H1299, HeLa whole cells lysate, DU145 xenograft

性能

应用

Our Abpromise guarantee covers the use of ab96168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
  • 序列相似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein activated inward rectifier potassium channel 1 antibody
    • G protein-activated inward rectifier potassium channel 1 antibody
    • GIRK-1 antibody
    • GIRK1 antibody
    • Inward rectifier K(+) channel Kir3.1 antibody
    • Inwardly rectifying potassium channel KIR3.1 antibody
    • inwardly rectifying subfamily J member 3 antibody
    • IRK3 antibody
    • IRK3_HUMAN antibody
    • Kcnf3 antibody
    • Kcnj3 antibody
    • KGA antibody
    • KGB1 antibody
    • Kir3.1 antibody
    • Potassium channel antibody
    • Potassium channel, inwardly rectifying subfamily J member 3 antibody
    • Potassium inwardly-rectifying channel, subfamily J, member 3 antibody
    see all

Anti-GIRK1 antibody 图像

  • All lanes : Anti-GIRK1 antibody (ab96168) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 57 kDa
  • Immunohistochemical analysis of paraffin-embedded DU145 xenograft, using ab96168 at 1:100 dilution.

Anti-GIRK1 antibody (ab96168)参考文献

ab96168 has not yet been referenced specifically in any publications.

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