概述

  • 产品名称Anti-GIRK1抗体
    参阅全部 GIRK1 一抗
  • 描述
    兔多克隆抗体to GIRK1
  • 特异性Detects endogenous levels of total GIRK1 protein
  • 经测试应用适用于: IHC-Fr, ICC/IF, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic non-phosphopeptide (Human) from around the phosphorylation site of serine 185 (KMSPQP)

  • 阳性对照
    • HeLa cells

性能

应用

Our Abpromise guarantee covers the use of ab61191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration. PubMed: 20569696
ICC/IF 1/500 - 1/1000.
ELISA 1/20000.

靶标

  • 功能This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
  • 序列相似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein activated inward rectifier potassium channel 1 antibody
    • G protein-activated inward rectifier potassium channel 1 antibody
    • GIRK-1 antibody
    • GIRK1 antibody
    • Inward rectifier K(+) channel Kir3.1 antibody
    • Inwardly rectifying potassium channel KIR3.1 antibody
    • inwardly rectifying subfamily J member 3 antibody
    • IRK3 antibody
    • IRK3_HUMAN antibody
    • Kcnf3 antibody
    • Kcnj3 antibody
    • KGA antibody
    • KGB1 antibody
    • Kir3.1 antibody
    • Potassium channel antibody
    • Potassium channel, inwardly rectifying subfamily J member 3 antibody
    • Potassium inwardly-rectifying channel, subfamily J, member 3 antibody
    see all

Anti-GIRK1 antibody 图像

  • Immunofluorescence analysis of HeLa cells using ab61191 at 1/500 dilution. Samples were treated -/+ immunising peptide.

Anti-GIRK1 antibody (ab61191)参考文献

This product has been referenced in:
  • Aiden AP  et al. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell 6:591-602 (2010). IHC-Fr ; Human . Read more (PubMed: 20569696) »

See 1 Publication for this product

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