概述

  • 产品名称
  • 描述
    兔多克隆抗体to GIGYF1
  • 经测试应用
    适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen, corresponding to amino acids 947-1022 (DTLEAKEFAK QFLERRAKQK ASQQRQQQQE AWLSSASLQT AFQANHSTKL GPGEGSKAKR RALMLHSDPS ILGYSL) of Human GIGYF1.

  • 阳性对照
    • Human rectum tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1.
  • 序列相似性
    Belongs to the PERQ family.
    Contains 1 GYF domain.
  • 结构域
    The GYF domain interacts with GRB10.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CDS2 antibody
    • GIGYF1 antibody
    • GRB10-interacting GYF protein 1 antibody
    • GYF1 antibody
    • PERQ amino acid-rich with GYF domain-containing protein 1 antibody
    • PERQ1 antibody
    • PERQ1_HUMAN antibody
    • Postmeiotic segregation increased 2-like 12 antibody
    • PP3360 antibody
    see all

图片

  • Immunofluorescent staining of Human cell line A-431 shows positivity in vesicles. Recommended concentration of ab121646 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121646, at 1/65 dilution, staining GIGYF1 in paraffin-embedded Human rectum tissue, by Immunohistochemistry.

文献

ab121646 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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