概述

  • 产品名称Anti-GHRHR抗体
    参阅全部 GHRHR 一抗
  • 描述
    兔多克隆抗体to GHRHR
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Rabbit, Horse, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 107-156 (

    PYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRR

    ) of Human GHRHR (NP_001009824).

  • 阳性对照
    • PANC1 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab98027 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
  • 组织特异性Pituitary gland.
  • 疾病相关Defects in GHRHR are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH.
  • 序列相似性Belongs to the G-protein coupled receptor 2 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GHRFR antibody
    • GHRH R antibody
    • GHRH receptor antibody
    • Ghrhr antibody
    • GHRHR_HUMAN antibody
    • GHRHRpsv antibody
    • GRF R antibody
    • GRF receptor antibody
    • GRFR antibody
    • Growth hormone releasing factor receptor antibody
    • Growth hormone releasing hormone receptor antibody
    • Growth hormone-releasing factor receptor antibody
    • Growth hormone-releasing hormone receptor antibody
    see all

Anti-GHRHR antibody 图像

  • Anti-GHRHR antibody (ab98027) at 1 µg/ml (in 5% skim milk / PBS buffer) + PANC1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 47 kDa

Anti-GHRHR antibody (ab98027)参考文献

ab98027 has not yet been referenced specifically in any publications.

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