概述

  • 产品名称Anti-GFM2抗体
    参阅全部 GFM2 一抗
  • 描述
    兔多克隆抗体to GFM2
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal region of human GFM2.

  • 阳性对照
    • Extracts from LOVO cells and RAW264.7 cells. A549 cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab74874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 87 kDa (predicted molecular weight: 87 kDa).
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.

靶标

  • 相关性GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.
  • 细胞定位Mitochondrial
  • 数据库链接
  • 别名
    • EF-G2mt antibody
    • EFG2 antibody
    • EFG2mt antibody
    • elongation factor G 2, mitochondrial antibody
    • Elongation factor G2 antibody
    • G elongation factor mitochondrial 2 antibody
    • GFM2 antibody
    • hEFG2 antibody
    • mEFG 2 antibody
    • mEFG2 antibody
    • Mitochondrial elongation factor G2 antibody
    • mitochondrial ribosome recycling factor 2 antibody
    • MRRF2 antibody
    • MST027 antibody
    • MSTP027 antibody
    • OTTHUMP00000222951 antibody
    • OTTHUMP00000222952 antibody
    • ribosome-releasing factor 2, mitochondrial antibody
    • RRF2 antibody
    • RRF2mt antibody
    see all

Anti-GFM2 antibody 图像

  • All lanes : Anti-GFM2 antibody (ab74874) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from RAW264.7 cells
    Lane 3 : extracts from LOVO cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 87 kDa
    Observed band size : 87 kDa
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.
  • ab74874, at a dilution of 1/500, staining GFM2 in A549 cells by Immunofluorescence in the absence (left image) or presence (right image) of the immunizing peptide.

Anti-GFM2 antibody (ab74874)参考文献

ab74874 has not yet been referenced specifically in any publications.

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