参阅全部 GERP 一抗
WB, IHC-Pmore details
Mouse, Rat, Dog, Human, Pig
Synthetic peptide: YGQPSTKHYVTS, corresponding to C terminal amino acids 540-551 of Human GERP.
- 常规说明Principal Names – TRIM8; GERP; RNF27; tripartite motif-containing 8; ring finger protein 27; tripartite motif protein TRIM8; glioblastoma expressed ring finger protein.
Official Gene Symbol - TRIM8.
GenBank Accession Number – NP_112174.
LocusLink ID - 81603 (human); 93679 (mouse).
Gene Ontology terms - zinc ion binding; molecular function unknown; biological process unknown; kinesin complex; nucleus; cellular component unknown.
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
Concentration information loading...
- 纯度IgG fraction
- 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Compatible Secondaries
- Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent concentration. Can be blocked with Human GERP peptide (ab23022). No signal obtained yet but low background observed in Human Brain and Human Kidney lysates at up to 1µg / ml.
||Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
- 功能Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.
- 组织特异性Widely expressed.
- 通路Protein modification; protein ubiquitination.
- 序列相似性Belongs to the TRIM/RBCC family.
Contains 2 B box-type zinc fingers.
Contains 1 RING-type zinc finger.
- 结构域The coiled coil domain is required for homodimerization.
The region immediately C-terminal to the RING motif is sufficient to mediate the interaction with SOCS1.
Information by UniProt
- AA408830 antibody
- BB006755 antibody
- Glioblastoma-expressed RING finger protein antibody
Anti-GERP antibody (ab4302)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"