Mouse, Rat, Dog, Human, Pig
Synthetic peptide: YGQPSTKHYVTS, corresponding to C terminal amino acids 540-551 of Human GERP.
Principal Names – TRIM8; GERP; RNF27; tripartite motif-containing 8; ring finger protein 27; tripartite motif protein TRIM8; glioblastoma expressed ring finger protein.
Official Gene Symbol - TRIM8.
GenBank Accession Number – NP_112174.
LocusLink ID - 81603 (human); 93679 (mouse).
Gene Ontology terms - zinc ion binding; molecular function unknown; biological process unknown; kinesin complex; nucleus; cellular component unknown.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
Concentration information loading...
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. Can be blocked with
Human GERP peptide (ab23022). No signal obtained yet but low background observed in Human Brain and Human Kidney lysates at up to 1µg / ml.
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.
Protein modification; protein ubiquitination.
Belongs to the TRIM/RBCC family.
Contains 2 B box-type zinc fingers. Contains 1 RING-type zinc finger.
The coiled coil domain is required for homodimerization.
The region immediately C-terminal to the RING motif is sufficient to mediate the interaction with SOCS1.
Information by UniProt
Glioblastoma-expressed RING finger protein antibody
has not yet been referenced specifically in any publications.
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