Anti-Germinal Center Kinase抗体(ab82870)

概述

  • 产品名称Anti-Germinal Center Kinase抗体
    参阅全部 Germinal Center Kinase 一抗
  • 描述
    兔多克隆抗体to Germinal Center Kinase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 216-265 (HLHPMRALML MSKSSFQPPK LRDKTRWTQN FHHFLKLALT KNPKKRPTAE) of human Germinal Center Kinase (NP_004570).

  • 阳性对照
    • Fetal liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab82870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 92 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.
  • 组织特异性Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CNH domain.
    Contains 1 protein kinase domain.
  • 细胞定位Cytoplasm. Basolateral cell membrane. Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B lymphocyte serine/threonine protein kinase antibody
    • B lymphocyte serine/threonine-protein kinase antibody
    • BL44 antibody
    • GC kinase antibody
    • GCK antibody
    • Germinal center kinase antibody
    • germinal centre kinase (GC kinase) antibody
    • M4K2_HUMAN antibody
    • Map4k2 antibody
    • MAPK/ERK kinase kinase kinase 2 antibody
    • MEK kinase kinase 2 antibody
    • MEKKK 2 antibody
    • Mitogen activated protein kinase kinase kinase kinase 2 antibody
    • Mitogen-activated protein kinase kinase kinase kinase 2 antibody
    • Rab8 interacting protein antibody
    • Rab8 interacting protein, formerly antibody
    • Rab8-interacting protein antibody
    • RAB8IP antibody
    • RAB8IP, formerly antibody
    see all

Anti-Germinal Center Kinase antibody 图像

  • Anti-Germinal Center Kinase antibody (ab82870) at 1 µg/ml + fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 92 kDa
    Observed band size : 89 kDa (why is the actual band size different from the predicted?)

Anti-Germinal Center Kinase antibody (ab82870)参考文献

ab82870 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82870.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"