概述

  • 产品名称Anti-Gemin 2抗体
    参阅全部 Gemin 2 一抗
  • 描述
    兔多克隆抗体to Gemin 2
  • 特异性ab124511 is predicted to not cross-react with other Gemin proteins. At least four isoforms of Gemin 2 are known to exist of which ab124511 recognizes the two longest isoforms (isoform 1 and isoform 2).
  • 经测试应用适用于: ICC/IF, WB, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human Gemin 2 (C terminal).
    Database link: O14893

  • 阳性对照
    • HeLa cells and cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab124511 is affinity chromatography purified via a peptide column.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab124511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 31 kDa.
ICC Use a concentration of 4 µg/ml.

靶标

  • 功能The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
  • 序列相似性Belongs to the gemin-2 family.
  • 细胞定位Nucleus > gem. Cytoplasm. Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs. Also found in the cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Component of gems 2 antibody
    • Gem (nuclear organelle) associated protein 2 antibody
    • Gem associated protein 2 antibody
    • GEMI2_HUMAN antibody
    • Gemin-2 antibody
    • gemin2 antibody
    • SIP 1 antibody
    • SIP-1 antibody
    • SIP1 antibody
    • SIP1 delta antibody
    • SIP1-delta antibody
    • SMN interacting protein 1 antibody
    • SMN interacting protein 1 delta antibody
    • SMN-interacting protein 1 antibody
    • Survival interacting protein 1 antibody
    • Survival of motor neuron protein interacting protein 1 antibody
    • Survival of motor neuron protein-interacting protein 1 antibody
    see all

Anti-Gemin 2 antibody 图像

  • Immunofluorescence of Gemin 2 in HeLa cells with ab124511 at 20 ug/mL.

  • Lane 1 : Anti-Gemin 2 antibody (ab124511) at 0.5 µg/ml
    Lane 2 : Anti-Gemin 2 antibody (ab124511) at 1 µg/ml

    Lane 1 : HeLa cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 31 kDa
  • ab124511 at 4 µg/ml staining Gemin 2 in HeLa cells by Immunocytochemistry.

Anti-Gemin 2 antibody (ab124511)参考文献

ab124511 has not yet been referenced specifically in any publications.

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