Anti-GDNF Receptor alpha 2抗体(ab6170)

概述

  • 产品名称Anti-GDNF Receptor alpha 2抗体
    参阅全部 GDNF Receptor alpha 2 一抗
  • 描述
    兔多克隆抗体to GDNF Receptor alpha 2
  • 特异性Specific to GFR alpha 2. No reaction with its homologues.
  • 经测试应用适用于: IHC-Fr, WBmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    PRVEKTPSLPDDLSD

    conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 376-390 of Rat GDNF family Receptor alpha 2.

  • 常规说明This antibody stains large neurons in the rat dorsal root ganglia. It has also proven useful for western blot of rat brain.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab6170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
WB
  • 应用说明Immunohistochemistry: 1/1,000
    Western Blot: 1/500-1,000
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • 靶标

    • 功能Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
      Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
    • 组织特异性Isoform 1 is found in both brain and placenta.
    • 序列相似性Belongs to the GDNFR family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • GDNF family receptor alpha 2 antibody
      • GDNF family receptor alpha-2 antibody
      • GDNF receptor alpha-2 antibody
      • GDNF receptor beta antibody
      • GDNFR beta antibody
      • GDNFR-alpha-2 antibody
      • GDNFR-beta antibody
      • GDNFRB antibody
      • GFR alpha 2 antibody
      • GFR-alpha-2 antibody
      • GFRA 2 antibody
      • Gfra2 antibody
      • GFRA2_HUMAN antibody
      • Glial cell line derived neurotrophic factor family receptor alpha2b antibody
      • Glial cell line derived neurotrophic factor receptor beta antibody
      • Neurturin receptor alpha antibody
      • NRTNR alpha antibody
      • NRTNR-alpha antibody
      • NTNR alpha antibody
      • NTNR-alpha antibody
      • NTNRA antibody
      • PI linked cell surface accessory protein antibody
      • PI linked cell-surface accessory protein antibody
      • RET ligand 2 antibody
      • RETL 2 antibody
      • RETL2 antibody
      • TGF beta related neurotrophic factor receptor 2 antibody
      • TGF-beta-related neurotrophic factor receptor 2 antibody
      • TRN receptor GPI anchored antibody
      • TRNR 2 antibody
      • TRNR2 antibody
      see all

    Anti-GDNF Receptor alpha 2 antibody (ab6170)参考文献

    ab6170 has not yet been referenced specifically in any publications.

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    Thank you for your enquiry. In answer to your questions. We state "centrifuge to remove any insoluble material" on the product datasheet because this product is whole serum and therefore prior to use it is a good idea to centrifuge the sera to remo...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"