Anti-GCNT3抗体(ab111371)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to GCNT3
  • 经测试应用
    适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human GCNT3.

  • 阳性对照
    • A549 cells and Human liver carcinoma tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab111371 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111371 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

靶标

  • 功能
    Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
  • 组织特异性
    Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.
  • 通路
    Protein modification; protein glycosylation.
  • 序列相似性
    Belongs to the glycosyltransferase 14 family.
  • 翻译后修饰
    N-glycosylated.
  • 细胞定位
    Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2010013H22Rik antibody
    • 2210021I22Rik antibody
    • 2210401J11Rik antibody
    • 3-galactosyl-O-glycosyl-glycoprotein beta-1 antibody
    • 6-N-acetylglucosaminyltransferase 3 antibody
    • 6-N-acetylglucosaminyltransferase antibody
    • Beta 1 3 galactosyl O glycosyl glycoprotein beta 1 6 N acetylglucosaminyltransferase 3 antibody
    • Beta-1 antibody
    • Beta1 6 N acetylglucosaminyltransferase 3 antibody
    • beta1 6 N acetylglucosaminyltransferase antibody
    • C2/4GnT antibody
    • C24GNT antibody
    • C2GnT M antibody
    • C2GnT mucin type antibody
    • C2GnT-M antibody
    • C2GnT-mucin type antibody
    • C2GnT2 antibody
    • C2GNTM antibody
    • Core 2 beta 1 6 N acetylglucosaminyltransferase II antibody
    • Core 2/core 4 beta 1 6 N acetylglucosaminyltransferase antibody
    • Core 2/core 4 beta-1 antibody
    • dI/C2/C4GnT antibody
    • EC 2.4.1.102 antibody
    • EC 2.4.1.150 antibody
    • GCNT3 antibody
    • GCNT3_HUMAN antibody
    • Glucosaminyl (N acetyl) transferase 3 antibody
    • Glucosaminyl (N acetyl) transferase 3 mucin type antibody
    • glucosaminyl (N-acetyl) transferase 3, mucin type antibody
    • GnT M antibody
    • GNTM antibody
    • hC2GnT M antibody
    • hC2GnT-M antibody
    • Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase antibody
    • OTTHUMP00000163601 antibody
    see all

图片

  • ab111371 at 1/100 dilution staining GCNT3 in A549 cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.
  • ab111371 at 1/50 dilution staining GCNT3 in paraffin-embedded Human Liver carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

文献

ab111371 has not yet been referenced specifically in any publications.

客户评价及客户问答

Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (Tumor)
Permeabilization
Yes - Triton X100
Specification
Tumor
Blocking step
BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: RT°C
Fixative
Paraformaldehyde
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提交于 Feb 09 2017

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