概述

  • 产品名称Anti-GBA3抗体
    参阅全部 GBA3 一抗
  • 描述
    兔多克隆抗体to GBA3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide, corresponding to a region within N terminal amino acids 71-120 (LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH) of Human GBA3 (NP_066024.1).

  • 阳性对照
    • HeLa cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab118947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
  • 组织特异性Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
  • 序列相似性Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
  • 翻译后修饰The N-terminus is blocked.
  • 细胞定位Cytoplasm > cytosol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CBG antibody
    • CBGL1 antibody
    • Cytosolic beta glucosidase antibody
    • Cytosolic beta glucosidase like protein 1 antibody
    • Cytosolic beta-glucosidase antibody
    • Cytosolic beta-glucosidase-like protein 1 antibody
    • GBA3 antibody
    • GBA3_HUMAN antibody
    • GLUC antibody
    • Glucosidase beta acid 3 antibody
    • Klotho related protein antibody
    • KLRP antibody
    see all

Anti-GBA3 antibody 图像

  • Anti-GBA3 antibody (ab118947) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 54 kDa

Anti-GBA3 antibody (ab118947)参考文献

ab118947 has not yet been referenced specifically in any publications.

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