概述

  • 产品名称Anti-GATA3抗体
    参阅全部 GATA3 一抗
  • 描述
    小鼠单克隆抗体to GATA3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: LGSHHTASPW NLSPFSKTSI HHGSPGPLSV YPPASSSSLS GGHASPHLFT FPPTPPKDVS PDPSLSTPGS AGSARQDEKE CLKYQVPLPD SMKLESSH, corresponding to amino acids 103-200 of human GATA3 (NP_001002295), with a proprietary tag

  • 阳性对照
    • The immunogen; HeLa nuclear extract; Jurkat cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab89776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
  • 组织特异性T-cells and endothelial cells.
  • 疾病相关Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.
  • 序列相似性Contains 2 GATA-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing.
  • 别名
    • GATA 3 antibody
    • GATA binding factor 3 antibody
    • GATA binding protein 3 antibody
    • GATA-binding factor 3 antibody
    • Gata3 antibody
    • GATA3_HUMAN antibody
    • HDR antibody
    • HDRS antibody
    • MGC2346 antibody
    • MGC5199 antibody
    • MGC5445 antibody
    • Trans acting T cell specific transcription factor GATA 3 antibody
    • Trans-acting T-cell-specific transcription factor GATA-3 antibody
    see all

Anti-GATA3 antibody 图像

  • Anti-GATA3 antibody (ab89776) at 1 µg/ml + immunogen at 0.2 µg

    Predicted band size : 48 kDa
  • Anti-GATA3 antibody (ab89776) at 1 µg/ml + HeLa nuclear extract at 50 µg

    Predicted band size : 48 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)
  • Anti-GATA3 antibody (ab89776) at 1 µg/ml + Jurkat cell lysate at 50 µg

    Predicted band size : 48 kDa
    Observed band size : 48 kDa
    Additional bands at : 37 kDa. We are unsure as to the identity of these extra bands.
  • Detection limit for ab89776 is approximately 0.03 ng/ml as a capture antibody.

Anti-GATA3 antibody (ab89776)参考文献

ab89776 has not yet been referenced specifically in any publications.

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