概述

  • 产品名称Anti-GATA3抗体
    参阅全部 GATA3 一抗
  • 描述
    兔多克隆抗体to GATA3
  • 经测试应用适用于: WB, IHC-Pmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 150-200 of Human GATA3 (NP_002042.1).

  • 阳性对照
    • Jurkat whole cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab124288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2500.
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
    • 组织特异性T-cells and endothelial cells.
    • 疾病相关Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.
    • 序列相似性Contains 2 GATA-type zinc fingers.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 形式There are 2 isoforms produced by alternative splicing.
    • 别名
      • GATA 3 antibody
      • GATA binding factor 3 antibody
      • GATA binding protein 3 antibody
      • GATA-binding factor 3 antibody
      • Gata3 antibody
      • GATA3_HUMAN antibody
      • HDR antibody
      • HDRS antibody
      • MGC2346 antibody
      • MGC5199 antibody
      • MGC5445 antibody
      • Trans acting T cell specific transcription factor GATA 3 antibody
      • Trans-acting T-cell-specific transcription factor GATA-3 antibody
      see all

    Anti-GATA3 antibody 图像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling GATA3 with ab124288 at 1/1000 (1µg/ml). Detection: DAB.
    • All lanes : Anti-GATA3 antibody (ab124288) at 0.4 µg/ml

      Lane 1 : Jurkat whole cell lysate at 50 µg
      Lane 2 : Jurkat whole cell lysate at 15 µg

      Developed using the ECL technique

      Exposure time : 3 minutes

    Anti-GATA3 antibody (ab124288)参考文献

    ab124288 has not yet been referenced specifically in any publications.

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