Anti-Gastrin抗体, prediluted (ab928)

概述

  • 产品名称
    Anti-Gastrin抗体, prediluted
    参阅全部 Gastrin 一抗
  • 描述
    兔多克隆抗体to Gastrin, prediluted
  • 经测试应用
    适用于: IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein conjugated to KLH.

性能

应用

Our Abpromise guarantee covers the use of ab928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
IHC-Fr
  • 应用说明
    This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
    No further titration is required.
    We suggest an incubation period of 30-60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user.
  • 靶标

    • 功能
      Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
    • 序列相似性
      Belongs to the gastrin/cholecystokinin family.
    • 翻译后修饰
      Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
      Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Component II antibody
      • G14 antibody
      • G17 antibody
      • G34 antibody
      • G52 antibody
      • G6 antibody
      • GAS antibody
      • Gast antibody
      • GAST_HUMAN antibody
      • Gastrin antibody
      • Gastrin component I antibody
      • Gastrin component II antibody
      • Gastrin component III antibody
      • Gastrin precursor antibody
      • Gastrin-14 antibody
      • Gastrin-17 antibody
      • Gastrin-34 antibody
      • Gastrin-52 antibody
      • Gastrin-6 antibody
      • Gastrin-71 antibody
      see all

    文献

    ab928 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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