Anti-gamma Synuclein抗体(ab46201)

概述

  • 产品名称Anti-gamma Synuclein抗体
    参阅全部 gamma Synuclein 一抗
  • 描述
    兔多克隆抗体to gamma Synuclein
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 to the C-terminus of Human gamma Synuclein.

    (Peptide available as ab46713.)

  • 阳性对照
    • This antibody gave a positive signal in Gamma Synuclein recombinant protein.

性能

应用

Our Abpromise guarantee covers the use of ab46201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa corresponding to the molecular weight of the full length Gamma Synuclein recombinant protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
    • 组织特异性Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
    • 序列相似性Belongs to the synuclein family.
    • 翻译后修饰Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
    • 细胞定位Cytoplasm > perinuclear region. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BCSG1 antibody
      • Breast cancer specific gene 1 protein antibody
      • Breast cancer specific protein 1 antibody
      • Breast cancer-specific gene 1 protein antibody
      • Gamma synuclein antibody
      • Gamma-synuclein antibody
      • Persyn antibody
      • PRSN antibody
      • SNCG antibody
      • SR antibody
      • Synoretin antibody
      • Synuclein gamma antibody
      • synuclein, gamma (breast cancer-specific protein 1) antibody
      • SYUG_HUMAN antibody
      see all

    Anti-gamma Synuclein antibody 图像

    • Anti-gamma Synuclein antibody (ab46201) at 0.5 µg/ml + Recombinant Human gamma Synuclein protein (ab48712) at 0.05 µg

      Secondary
      Goat polyclonal to rabbit IgG - H&L - Pre adsorbed (HRP) at 1/3000 dilution

      Performed under reducing conditions.

      Observed band size : 15 kDa (why is the actual band size different from the predicted?)

    Anti-gamma Synuclein antibody (ab46201)参考文献

    ab46201 has not yet been referenced specifically in any publications.

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