Anti-gamma C Crystallin抗体(ab54665)

概述

  • 产品名称Anti-gamma C Crystallin抗体
    参阅全部 gamma C Crystallin 一抗
  • 描述
    小鼠单克隆抗体to gamma C Crystallin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: SIRSCCLIPQ TVSHRLRLYE REDHKGLMME LSEDCPSIQD RFHLSEIRSL HVLEGCWVLY ELPNYRGRQY LLRPQEYRRC QDWGAMDAKA GSLRRVVDLY , corresponding to amino acids 75-174 of Human gamma C Crystallin

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab54665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 - 5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Crystallins are the dominant structural components of the vertebrate eye lens.
    • 疾病相关Defects in CRYGC are a cause of cataract autosomal dominant (ADC) [MIM:604219]. Cataract is an opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Cataract is the most common treatable cause of visual disability in childhood.
      Defects in CRYGC are a cause of cataract Coppock-like (CCL) [MIM:604307]. A congenital pulverulent disk-like opacity involving the embryonic nucleus with many tiny white dots in the lamellar portion of the lens. It is usually bilateral and dominantly inherited.
    • 序列相似性Belongs to the beta/gamma-crystallin family.
      Contains 4 beta/gamma crystallin 'Greek key' domains.
    • 结构域Has a two-domain beta-structure, folded into four very similar Greek key motifs.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CATARACT, VARIABLE ZONULAR PULVERULENT antibody
      • CCL antibody
      • CRGC_HUMAN antibody
      • CRYG 3 antibody
      • Cryg 5 antibody
      • Cryg antibody
      • CRYG3 antibody
      • CRYGC antibody
      • Crystallin gamma 3 antibody
      • Crystallin gamma C antibody
      • Gamma C crystallin antibody
      • Gamma crystallin 2 1 antibody
      • Gamma crystallin 3 antibody
      • Gamma crystallin C antibody
      • Gamma-C-crystallin antibody
      • Gamma-crystallin 2-1 antibody
      • Gamma-crystallin 3 antibody
      • Gamma-crystallin C antibody
      • Gammab cry antibody
      • Len antibody
      see all

    Anti-gamma C Crystallin antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab54665 gamma C Crystallin antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-gamma C Crystallin antibody (ab54665)参考文献

    ab54665 has not yet been referenced specifically in any publications.

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