概述

  • 产品名称Anti-gamma Adaptin抗体
    参阅全部 gamma Adaptin 一抗
  • 描述
    兔多克隆抗体to gamma Adaptin
  • 经测试应用适用于: IP, WB, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    IRLRELIRTIRTARTQAEER

    , corresponding to N terminal amino acids 4-23 of gamma Adaptin

  • 阳性对照
    • Rat brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: Whole serum
  • 纯度Whole antiserum
  • 纯化说明0.1ml filtered lyophilized serum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab21980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
WB
IHC-Fr
IHC-P
  • 应用说明IHC-Fr: 1/200 - 1/2000. depending on tissue and detection method.
    IHC-P: 1/200 - 1/2000. depending on tissue and detection method.
    IP: Use at an assay dependent dilution.
    WB: 1/1000 - 1/4000. depending on detection method. Predicted molecular weight: 91 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    • 组织特异性Widely expressed.
    • 序列相似性Belongs to the adaptor complexes large subunit family.
      Contains 1 GAE domain.
    • 细胞定位Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Adapter-related protein complex 1 subunit gamma-1 antibody
      • Adaptor protein complex AP 1 gamma 1 subunit antibody
      • Adaptor protein complex AP 1 subunit gamma 1 antibody
      • Adaptor protein complex AP-1 subunit gamma-1 antibody
      • Adaptor related protein complex 1 gamma 1 subunit antibody
      • ADTG antibody
      • AP 1 complex subunit gamma 1 antibody
      • AP-1 complex subunit gamma-1 antibody
      • AP1G1 antibody
      • AP1G1_HUMAN antibody
      • CLAPG1 antibody
      • Clathrin assembly protein complex 1 gamma 1 large chain antibody
      • Clathrin assembly protein complex 1 gamma large chain antibody
      • Clathrin assembly protein complex 1 gamma-1 large chain antibody
      • Clathrin associated/assembly/adaptor protein large gamma 1 antibody
      • Gamma1 adaptin antibody
      • Gamma1-adaptin antibody
      • Golgi adaptor HA1/AP1 adaptin gamma subunit antibody
      • Golgi adaptor HA1/AP1 adaptin subunit gamma 1 antibody
      • Golgi adaptor HA1/AP1 adaptin subunit gamma-1 antibody
      • MGC18255 antibody
      see all

    Anti-gamma Adaptin antibody 图像

    • All lanes : Anti-gamma Adaptin antibody (ab21980) at 1/2000 dilution

      Lane 1 : Ramos (Human Burkitt's lymphoma cell line) Whole Cell Lysate
      Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Predicted band size : 91 kDa
      Observed band size : 100 kDa (why is the actual band size different from the predicted?)

    Anti-gamma Adaptin antibody (ab21980)参考文献

    This product has been referenced in:
    • Yi L  et al. HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking. J Biol Chem 285:30884-905 (2010). Read more (PubMed: 20622010) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab21980.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"