概述

  • 产品名称
  • 描述
    山羊多克隆抗体to GALR2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    C-RYPLHSRELRTPRN

    , corresponding to internal sequence amino acids 128-141 of Human GALR2

  • 阳性对照
    • Human Heart lysate.

性能

应用

Our Abpromise guarantee covers the use of ab59029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明
    Peptide ELISA: antibody detection limit dilution 1:4,000.

    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Receptor for the hormone galanin and for GALP. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
    • 组织特异性
      Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine.
    • 序列相似性
      Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位
      Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • GAL2-R antibody
      • GAL2R antibody
      • Galanin receptor 2 antibody
      • Galanin receptor type 2 antibody
      • GALNR2 antibody
      • GALR-2 antibody
      • GALR2 antibody
      • GALR2_HUMAN antibody
      • MGC125983 antibody
      • MGC125984 antibody
      see all

    图片

    • Anti-GALR2 antibody (ab59029) at 0.3 µg/ml + Human Heart lysate (35µg protein in RIPA buffer)

      Predicted band size : 42 kDa
      Observed band size : 42 kDa

    实验方案

    文献

    This product has been referenced in:
    • He L  et al. Galanin receptor 2 mediates antifibrogenic effects of galanin on hepatic stellate cells. Exp Ther Med 12:3375-3380 (2016). ICC/IF ; Rat . Read more (PubMed: 27882166) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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