概述

  • 产品名称
  • 描述
    兔多克隆抗体to GALNT7
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 24-485 of Human GALNT7 (NP_059119).

  • 阳性对照
    • A431 whole cell lysate; 293T, H1299, HeLaS3, HepG2, Molt-4 and Raji cell lysates

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab97645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 75 kDa.

靶标

  • 功能
    Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
  • 组织特异性
    Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
  • 通路
    Protein modification; protein glycosylation.
  • 序列相似性
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • 结构域
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 细胞定位
    Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GalNAc T7 antibody
    • GalNAc-T7 antibody
    • GalNAcT7 antibody
    • GALNT 7 antibody
    • Galnt7 antibody
    • GALT7_HUMAN antibody
    • N acetylgalactosaminyltransferase 7 antibody
    • N-acetylgalactosaminyltransferase 7 antibody
    • Polypeptide GalNAc transferase 7 antibody
    • Polypeptide N acetylgalactosaminyltransferase 7 antibody
    • pp GaNTase 7 antibody
    • pp-GaNTase 7 antibody
    • Protein UDP acetylgalactosaminyltransferase 7 antibody
    • Protein-UDP acetylgalactosaminyltransferase 7 antibody
    • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7 antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 antibody
    see all

图片

  • Anti-GALNT7 antibody (ab97645) at 1/10000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 75 kDa

实验方案

文献

ab97645 has not yet been referenced specifically in any publications.

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