概述

  • 产品名称
  • 描述
    兔多克隆抗体to GALNT2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Zebrafish
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 55-339 of Human GALNT2 (NP_004472)

  • 阳性对照
    • HepG2, Molt-4 and Raji cells

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG

应用

Our Abpromise guarantee covers the use of ab97741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 65 kDa.

靶标

  • 功能
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.
  • 组织特异性
    Widely expressed.
  • 通路
    Protein modification; protein glycosylation.
  • 序列相似性
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • 结构域
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 细胞定位
    Golgi apparatus > Golgi stack membrane. Secreted. Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GalNAc T2 antibody
    • GalNAc-T2 antibody
    • Galnt2 antibody
    • GALT2_HUMAN antibody
    • GaNTase 2 antibody
    • Polypeptide GalNAc transferase 2 antibody
    • Polypeptide N acetylgalactosaminyltransferase 2 antibody
    • Polypeptide N acetylgalactosaminyltransferase 2 soluble form antibody
    • Polypeptide N-acetylgalactosaminyltransferase 2 soluble form antibody
    • pp GaNTase 2 antibody
    • pp-GaNTase 2 antibody
    • Protein UDP acetylgalactosaminyltransferase 2 antibody
    • Protein-UDP acetylgalactosaminyltransferase 2 antibody
    • UDP GalNAc transferase 2 antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 (GalNAc T2) antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2 antibody
    see all

图片

  • Anti-GALNT2 antibody (ab97741) at 1/500 dilution + Molt-4 whole cell lysate at 30 µg

    Predicted band size : 65 kDa

实验方案

文献

ab97741 has not yet been referenced specifically in any publications.

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