概述

  • 产品名称Anti-GALNT14抗体
    参阅全部 GALNT14 一抗
  • 描述
    小鼠多克隆抗体to GALNT14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    GALNT14 (NP_078848, 1 a.a. ~ 552 a.a) full length human protein

  • 阳性对照
    • GALNT14-transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab68928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 64 kDa.

靶标

  • 功能Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
  • 组织特异性Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bladder, uterus, placenta, testis, ovary, skeletal muscle, leukocyte, B-cell, bone marrow, fetal brain, fetal thymus, fetal lung, fetal liver, fetal small intestine, fetal spleen, fetal skeletal and fetus.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • 结构域There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 细胞定位Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GalNAc T14 antibody
    • GalNAc-T14 antibody
    • Galnt14 antibody
    • GLT14_HUMAN antibody
    • Polypeptide GalNAc transferase 14 antibody
    • Polypeptide N acetylgalactosaminyltransferase 14 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 14 antibody
    • pp GaNTase 14 antibody
    • pp-GaNTase 14 antibody
    • Protein UDP acetylgalactosaminyltransferase 14 antibody
    • Protein-UDP acetylgalactosaminyltransferase 14 antibody
    • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 antibody
    see all

Anti-GALNT14 antibody 图像

  • All lanes : Anti-GALNT14 antibody (ab68928) at 1/500 dilution

    Lane 1 : GALNT14-transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 64 kDa

Anti-GALNT14 antibody (ab68928)参考文献

ab68928 has not yet been referenced specifically in any publications.

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