概述

  • 产品名称Anti-GALNT11抗体
    参阅全部 GALNT11 一抗
  • 描述
    兔多克隆抗体to GALNT11
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 98-147 (LGMIFNERDQ ELRDLGYQKH AFNMLISNRL GYHRDVPDTR NAECRRKSYP) of Rat GALNT11 (NP_955425).

  • 阳性对照
    • Rat heart lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin.
  • 组织特异性Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • 结构域There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • 细胞定位Golgi apparatus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A430075I06Rik antibody
    • AI648252 antibody
    • E430002F06Rik antibody
    • FLJ21634 antibody
    • GalNAc Transferase 11 antibody
    • GalNAc-T11 antibody
    • GalNAcT11 antibody
    • GALNT11 antibody
    • GLT11_HUMAN antibody
    • MGC71630 antibody
    • Polypeptide GalNAc transferase 11 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • pp-GaNTase 11 antibody
    • Protein-UDP acetylgalactosaminyltransferase 11 antibody
    • tcag7.1057 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) antibody
    see all

Anti-GALNT11 antibody 图像

  • Anti-GALNT11 antibody (ab110861) at 1 µg/ml + Rat heart lysate at 10 µg

    Predicted band size : 69 kDa

Anti-GALNT11 antibody (ab110861)参考文献

ab110861 has not yet been referenced specifically in any publications.

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