概述

  • 产品名称Anti-Galectin 3抗体
    参阅全部 Galectin 3 一抗
  • 描述
    兔多克隆抗体to Galectin 3
  • 经测试应用适用于: ELISA, WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region from the internal domain of Human Galectin 3 (NP_002297.2).

  • 阳性对照
    • HeLa cell extract; Human Colon (epithelium) and Spleen (macrophages); NIH 3T3 cells.

性能

应用

Our Abpromise guarantee covers the use of ab118851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 26 kDa.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
  • 组织特异性A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
  • 序列相似性Contains 1 galectin domain.
  • 细胞定位Nucleus. Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 35 kDa lectin antibody
    • Carbohydrate binding protein 35 antibody
    • Carbohydrate-binding protein 35 antibody
    • CBP 35 antibody
    • CBP35 antibody
    • Gal-3 antibody
    • GAL3 antibody
    • Galactose-specific lectin 3 antibody
    • Galactoside-binding protein antibody
    • GALBP antibody
    • Galectin 3 internal gene,included antibody
    • Galectin-3 antibody
    • Galectin3 antibody
    • GALIG antibody
    • GBP antibody
    • IgE binding protein antibody
    • IgE-binding protein antibody
    • L 31 antibody
    • L 34 antibody
    • L-31 antibody
    • L-34 galactoside-binding lectin antibody
    • L31 antibody
    • Laminin-binding protein antibody
    • Lectin L-29 antibody
    • Lectin, galactose binding, soluble 3 antibody
    • LEG3_HUMAN antibody
    • LGALS2 antibody
    • LGALS3 antibody
    • MAC 2 antigen antibody
    • Mac-2 antibody
    • Mac-2 antigen antibody
    • MAC2 antibody
    • Macrophage galactose-specific lectin antibody
    • MGC105387 antibody
    see all

Anti-Galectin 3 antibody 图像

  • All lanes : Anti-Galectin 3 antibody (ab118851) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : HeLA cell extract with synthesized peptide


    Predicted band size : 26 kDa
  • ab118851, at 10 µg/ml, staining Galectin 3 in Formalin-fixed, Paraffin-embedded Human Colon, eipithelium tissue by Immunohistochemistry.
  • ab118851, at 10 µg/ml, staining Galectin 3 in Formalin-fixed, Paraffin-embedded Human Spleen (macrophages) tissue by Immunohistochemistry.
  • ab118851 at 1/100 dilution staining Galectin 3 in NIH 3T3 cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.

Anti-Galectin 3 antibody (ab118851)参考文献

This product has been referenced in:
  • Zhang H  et al. Galectin-3 as a marker and potential therapeutic target in breast cancer. PLoS One 9:e103482 (2014). IHC-P ; Human . Read more (PubMed: 25254965) »

See 1 Publication for this product

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